Blephex a new Blepharitis Treatment

Blephex, a new Blepharitis Treatment has just been launched and may be of help for people with sore eyes. Many patients suffer from blepharitis or sore eye lids. These can cause irritable and dry eyes.  The mainstay of treatment is heating the eye lids, followed by massage and then eye lid cleansing with tea tree oil shampoo. This generally works however the heating needs to be at least 10 minutes to fully open the meibomian glands. The face needs to become hot and sweaty before the waxy material in the glands melts and the pores open. Once the pores are open massage and cleansing with a baby shampoo is useful. Finally drops can reduce inflammation and infection in the eye lids. Do ask your ophthalmologist about these as the best can only be got on prescription.

A new lid massage machine has just been launched by Blephex http://www.blephex.com, this looks interesting and potentially useful in cleaning the eye- lids and massaging the meibomian glands. We will be trialing this with patients over the next few weeks – do ask about our progress.

Also check out our latest – Blepharitis patient information. http://theeyesite.info/treatments/ophthalmics-lid-care/

Richard Newsom

Research

1: Gosse E, Newsom R, Lochhead J. The incidence and distribution of iatrogenic
retinal tears in 20-gauge and 23-gauge vitrectomy. Eye (Lond). 2012
Jan;26(1):140-3. doi: 10.1038/eye.2011.289. Epub 2011 Nov 18. PubMed PMID:
22094297; PubMed Central PMCID: PMC3259601.

2: Haller JA, Bandello F, Belfort R Jr, Blumenkranz MS, Gillies M, Heier J,
Loewenstein A, Yoon YH, Jiao J, Li XY, Whitcup SM; Ozurdex GENEVA Study Group, Li
J. Dexamethasone intravitreal implant in patients with macular edema related to
branch or central retinal vein occlusion twelve-month study results.
Ophthalmology. 2011 Dec;118(12):2453-60. doi: 10.1016/j.ophtha.2011.05.014. Epub
2011 Jul 20. PubMed PMID: 21764136.

3: Haller JA, Bandello F, Belfort R Jr, Blumenkranz MS, Gillies M, Heier J,
Loewenstein A, Yoon YH, Jacques ML, Jiao J, Li XY, Whitcup SM; OZURDEX GENEVA
Study Group. Randomized, sham-controlled trial of dexamethasone intravitreal
implant in patients with macular edema due to retinal vein occlusion.
Ophthalmology. 2010 Jun;117(6):1134-1146.e3. doi: 10.1016/j.ophtha.2010.03.032.
Epub 2010 Apr 24. PubMed PMID: 20417567.

4: Hornan DM, Madhusudhana KC, Newsom RS. Optometric telemedicine:
community-based screening for choroidal neovascularisation. Br J Ophthalmol. 2010
Mar;94(3):393-4. doi: 10.1136/bjo.2008.155754. PubMed PMID: 20215388.

5: Madhusudhana KC, Newsom RS. Bevacizumab: a new hope? Eye (Lond). 2009
Sep;23(9):1755-7. doi: 10.1038/sj.eye.6702937. PubMed PMID: 19741717.

6: Hannan SR, Madhusudhana KC, Newsom RS. The ring sign in patients with pigment
epithelial detachments. Ophthalmic Surg Lasers Imaging. 2009 Jan-Feb;40(1):85-6.
PubMed PMID: 19205507.

7: Benson SE, Ratcliffe S, VAN Raders P, Schlottmann PG, Khan I, Newsom R,
Langford RM, Charteris DG. A RANDOMISED COMPARISON OF PARECOXIB/VALDECOXIB AND
PLACEBO FOR THE PREVENTION OF CYSTOID MACULAR EDEMA AFTER SCLERAL BUCKLING
SURGERY. Retina. 2008 Dec 11. [Epub ahead of print] PubMed PMID: 19092729.

8: Khandhadia S, Madhusudhana KC, Kostakou A, Forrester JV, Newsom RS. Use of
Optomap for retinal screening within an eye casualty setting. Br J Ophthalmol.
2009 Jan;93(1):52-5. doi: 10.1136/bjo.2008.148072. Epub 2008 Oct 29. PubMed PMID:
18971233.

9: Owen CG, Newsom RS, Rudnicka AR, Barman SA, Woodward EG, Ellis TJ. Diabetes
and the tortuosity of vessels of the bulbar conjunctiva. Ophthalmology. 2008
Jun;115(6):e27-32. doi: 10.1016/j.ophtha.2008.02.009. PubMed PMID: 18423868.

10: Estabrook EJ, Madhusudhana KC, Hannan SR, Newsom RS. Can optical coherence
tomography predict the outcome of laser photocoagulation for diabetic macular
edema? Ophthalmic Surg Lasers Imaging. 2007 Nov-Dec;38(6):478-83. PubMed PMID:
18050810.

11: Rogers S, Madhusudhana KC, Kang HK, Luff AJ, Canning CR, Newsom RS. Combined
phacovitrectomy for macular hole: long-term results. Ophthalmic Surg Lasers
Imaging. 2007 Nov-Dec;38(6):452-6. PubMed PMID: 18050806.

12: Madhusudhana KC, Hannan SR, Williams CP, Goverdhan SV, Rennie C, Lotery AJ,
Luff AJ, Newsom RS. Intravitreal bevacizumab (Avastin) for the treatment of
choroidal neovascularization in age-related macular degeneration: results from
118 cases. Br J Ophthalmol. 2007 Dec;91(12):1716-7. PubMed PMID: 18024821; PubMed
Central PMCID: PMC2095533.

13: Madhusudhana KC, Hossain P, Thiagarajan M, Newsom RS. Use of anterior segment
optical coherence tomography in a penetrating eye injury. Br J Ophthalmol. 2007
Jul;91(7):982-3. PubMed PMID: 17576718; PubMed Central PMCID: PMC1955674.

14: Hannan SR, Madhusudhana KC, Lotery AJ, Newsom RS. Retinal pigment epithelial
tear following intravitreal bevacizumab for choroidal neovascular membrane due to
age-related macular degeneration. Br J Ophthalmol. 2007 Jul;91(7):977-8. PubMed
PMID: 17576713; PubMed Central PMCID: PMC1955628.

15: Goverdhan SV, Hannan S, Newsom RB, Luff AJ, Griffiths H, Lotery AJ. An
analysis of the CFH Y402H genotype in AMD patients and controls from the UK, and
response to PDT treatment. Eye (Lond). 2008 Jun;22(6):849-54. Epub 2007 Apr 27.
PubMed PMID: 17464302.

16: Madhusudhana KC, Newsom RS. Central retinal vein occlusion: the therapeutic
options. Can J Ophthalmol. 2007 Apr;42(2):193-5. PubMed PMID: 17392840.

17: Konstantopoulos A, Williams CP, Newsom RS, Luff AJ. Ocular morbidity
associated with intravitreal triamcinolone acetonide. Eye (Lond). 2007
Mar;21(3):317-20. Epub 2006 May 19. PubMed PMID: 16710433.

18: Sinclair NE, Booth A, Clover A, Newsom R. Argon laser photocoagulation for
diabetic macular oedema. Eye (Lond). 2006 Dec;20(12):1471-2. Epub 2006 May 12.
PubMed PMID: 16691259.

19: Roberts E, Madhusudhana KC, Newsom R, Cullis JO. Blindness due to angioid
streaks in congenital dyserythropoietic anaemia type I. Br J Haematol. 2006
Jun;133(5):456. PubMed PMID: 16681633.

20: Cuthbertson F, Newsom R. UK retinopathy of prematurity treatment survey. Eye
(Lond). 2007 Feb;21(2):156-7. Epub 2006 Jan 27. PubMed PMID: 16440020.

21: Jain S, Newsom RS, McHugh JD. Treatment of retinal breaks with large-spot
diode laser photocoagulation. Ophthalmic Surg Lasers Imaging. 2005
Nov-Dec;36(6):514-7. PubMed PMID: 16355959.

22: Clifford L, Newsom RS. Spontaneous cystoid macula oedema in chronic
granulomatous disease: a new posterior segment sign. Eye (Lond). 2006
Sep;20(9):1111-3. Epub 2005 Nov 25. PubMed PMID: 16311530.

23: Newsom RS, Johnston R, Sullivan P, Aylward B, Holder G, Gregor Z. Visual loss
following silicone oil removal. Br J Ophthalmol. 2005 Dec;89(12):1668. PubMed
PMID: 16299160; PubMed Central PMCID: PMC1772969.

24: Owen CG, Newsom RS, Rudnicka AR, Ellis TJ, Woodward EG. Vascular response of
the bulbar conjunctiva to diabetes and elevated blood pressure. Ophthalmology.
2005 Oct;112(10):1801-8. PubMed PMID: 16111757.

25: Clifford L, Sievers R, Salmon A, Newsom RS. Central retinal artery occlusion:
association with patent foramen ovale. Eye (Lond). 2006 Jun;20(6):736-8. Epub
2005 Jun 17. PubMed PMID: 15999129.

26: Newsom RS, McAlister JC, Saeed M, El-Ghonemy K, McHugh JD. Results 28 months
following transpupillary thermotherapy for classic and occult choroidal
neovascularization in patients with age-related macular degeneration. Ophthalmic
Surg Lasers Imaging. 2005 Mar-Apr;36(2):94-102. PubMed PMID: 15792308.

27: Newsom RS, Johnston R, Sullivan PM, Aylward GB, Holder GE, Gregor ZJ. Sudden
visual loss after removal of silicone oil. Retina. 2004 Dec;24(6):871-7. PubMed
PMID: 15579983.

28: Cuthbertson FM, Newsom RS, Wainwright AC. Kinetic anaesthesia for laser
surgery. Eye (Lond). 2005 Nov;19(11):1205-7. PubMed PMID: 15543180.

29: Costen MT, Newsom RS, Wainwright AC, Luff AJ, Canning CR. Expanding role of
local anaesthesia in vitreoretinal surgery. Eye (Lond). 2005 Jul;19(7):755-61.
PubMed PMID: 15389283.

30: Jogiya A, Newsom RS. Giant retinal pigment epithelium rip secondary to
subretinal proliferative vitreoretinopathy. Eye (Lond). 2004 Sep;18(9):960-2.
PubMed PMID: 15037891.

31: Ong GL, Ripley LG, Newsom RS, Cooper M, Casswell AG. Screening for
sight-threatening diabetic retinopathy: comparison of fundus photography with
automated color contrast threshold test. Am J Ophthalmol. 2004 Mar;137(3):445-52.
PubMed PMID: 15013866.

32: Costen MT, Newsom RS, Parkin B, Marsh CS, Mehta RL, Luff AJ, Canning CR.
Effect of video display on the grading of diabetic retinopathy. Eye (Lond). 2004
Feb;18(2):169-74. PubMed PMID: 14762410.

33: Newsom RS, Austin JS, Fini ME, Reichel E. Large spot endolaser for retinal
photocoagulation and transvitreal thermotherapy. Ophthalmic Surg Lasers Imaging.
2004 Jan-Feb;35(1):26-30. PubMed PMID: 14750760.

34: Marsh CS, Marden B, Newsom R. Severe retinopathy of prematurity (ROP) in a
premature baby treated with sildenafil acetate (Viagra) for pulmonary
hypertension. Br J Ophthalmol. 2004 Feb;88(2):306-7. PubMed PMID: 14736800;
PubMed Central PMCID: PMC1772024.

35: Ong GL, Ripley LG, Newsom RS, Casswell AG. Assessment of colour vision as a
screening test for sight threatening diabetic retinopathy before loss of vision.
Br J Ophthalmol. 2003 Jun;87(6):747-52. PubMed PMID: 12770974; PubMed Central
PMCID: PMC1771697.

36: Cook HL, Newsom RS, Mensah E, Saeed M, James D, Ffytche TJ. Entonox as an
analgesic agent during panretinal photocoagulation. Br J Ophthalmol. 2002
Oct;86(10):1107-8. PubMed PMID: 12234887; PubMed Central PMCID: PMC1771318.

37: Clarke J, Newsom R, Canning C. Ocular trauma with small framed spectacles. Br
J Ophthalmol. 2002 Apr;86(4):484. PubMed PMID: 11914236; PubMed Central PMCID:
PMC1771106.

38: Newsom R, Luff A, Wainwright C, Canning C. UK survey of attitudes to local
anaesthesia for vitreoretinal surgery. Eye (Lond). 2001 Dec;15(Pt 6):708-11.
PubMed PMID: 11826987.

39: Knight HM, Newsom RB, Canning CR, Luff AJ, Wainwright AC. Local anaesthesia
for vitreoretinal surgery: an audit of patient and surgical experience. Eur J
Ophthalmol. 2001 Oct-Dec;11(4):366-71. PubMed PMID: 11820309.

40: Newsom R. TTT and CNV. Br J Ophthalmol. 2001 Oct;85(10):1268-9. PubMed PMID:
11567975; PubMed Central PMCID: PMC1723733.

41: Newsom RS, Clover A, Costen MT, Sadler J, Newton J, Luff AJ, Canning CR.
Effect of digital image compression on screening for diabetic retinopathy. Br J
Ophthalmol. 2001 Jul;85(7):799-802. PubMed PMID: 11423452; PubMed Central PMCID:
PMC1724040.

42: Newsom RS, Wainwright AC, Canning CR. Local anaesthesia for 1221
vitreoretinal procedures. Br J Ophthalmol. 2001 Feb;85(2):225-7. PubMed PMID:
11159492; PubMed Central PMCID: PMC1723861.

43: Newsom RS, McAlister JC, Saeed M, McHugh JD. Transpupillary thermotherapy
(TTT) for the treatment of choroidal neovascularisation. Br J Ophthalmol. 2001
Feb;85(2):173-8. Erratum in: Br J Ophthalmol 2001 Apr;85(4):505. PubMed PMID:
11159481; PubMed Central PMCID: PMC1723824.

44: Newsom R, Moate B, Casswell T. Screening for diabetic retinopathy using
digital colour photography and oral fluorescein angiography. Eye (Lond). 2000
Aug;14 ( Pt 4):579-82. PubMed PMID: 11040903.

45: Rai P, Newsom R, Mireskandari K, McHugh D. Endophthalmitis following globe
perforation with a hypodermic needle. Br J Ophthalmol. 2000 Jul;84(7):799. PubMed
PMID: 11032433; PubMed Central PMCID: PMC1723545.

46: Newsom RS, Sinthanayothin C, Boyce J, Casswell AG, Williamson TH. Clinical
evaluation of ‘local contrast enhancement’ for oral fluorescein angiograms. Eye
(Lond). 2000 Jun;14 ( Pt 3A):318-23. PubMed PMID: 11026992.

47: Newsom RS, Ong GL, Jackson TL, Coldrick I, Ripley LG, Fisher M, Casswell AG.
Screening for CMV retinitis using chromatic discrimination thresholds and
achromatic contrast sensitivity. Br J Ophthalmol. 2000 Aug;84(8):877-80. PubMed
PMID: 10906095; PubMed Central PMCID: PMC1723611.

48: Newsom RS, Williamson TH. Globe perforation with frameless spectacles. Br J
Ophthalmol. 2000 Jun;84(6):668-9. Review. PubMed PMID: 10896414; PubMed Central
PMCID: PMC1723506.

49: Newsom R, Ayliffe W, Dhar-Munshi S, Kirkham N, Liu C. Management of corneal
opacification associated with epibulbar choristomata. Br J Ophthalmol. 1999
Dec;83(12):1404-5. PubMed PMID: 10660312; PubMed Central PMCID: PMC1722915.

50: Cook HL, Newsom R, Long V, Smith SA, Shilling JS, Stanford MR. Natural
history of diabetic macular streak exudates: evidence from a screening programme.
Br J Ophthalmol. 1999 May;83(5):563-6. PubMed PMID: 10216055; PubMed Central
PMCID: PMC1723041.

51: Newsom RS, Simcock P, Zambarakji H. Cerebral metastasis presenting with
altitudinal field defect. J Neuroophthalmol. 1999 Mar;19(1):10-1. PubMed PMID:
10098541.

52: Newsom R, Casswell T, O’Moore E, Fisher M. Cystoid macular oedema in patients
with AIDS and cytomegalovirus retinitis on highly active antiretroviral therapy.
Br J Ophthalmol. 1998 Apr;82(4):456-7. PubMed PMID: 9640201; PubMed Central
PMCID: PMC1722569.

53: Newsom RS, Oberstein SL, Falcon MG. An unusual corneal injury. Br J
Ophthalmol. 1996 Dec;80(12):1112-3. PubMed PMID: 9059284; PubMed Central PMCID:
PMC505717.

54: Watts P, Newsom R, McAllister J. Sphenoidal ridge meningioma masquerade:
glaucoma with a sphenoidal ridge meningioma. Eye (Lond). 1996;10 ( Pt 5):629-34.
PubMed PMID: 8977795.

55: Tomlin EA, Newsom RS, Davis AR. The outcome of strabismus surgery in
childhood exotropia. Eye (Lond). 1996;10 ( Pt 1):151. PubMed PMID: 8925940.

56: Newsom RS, Trew DR, Leonard TJ. Bilateral buried optic nerve drusen
presenting with central retinal artery occlusion at high altitude. Eye (Lond).
1995;9 ( Pt 6):806-8. PubMed PMID: 8849557.

57: Chen HC, Newsom RS, Patel V, Cassar J, Mather H, Kohner EM. Retinal blood
flow changes during pregnancy in women with diabetes. Invest Ophthalmol Vis Sci.
1994 Jul;35(8):3199-208. PubMed PMID: 8045714.

58: Patel V, Rassam S, Newsom R, Wiek J, Kohner E. Retinal blood flow in diabetic
retinopathy. BMJ. 1992 Sep 19;305(6855):678-83. PubMed PMID: 1393111; PubMed
Central PMCID: PMC1882919.

59: Newsom RS, Sullivan PM, Rassam SM, Jagoe R, Kohner EM. Retinal vessel
measurement: comparison between observer and computer driven methods. Graefes
Arch Clin Exp Ophthalmol. 1992;230(3):221-5. PubMed PMID: 1597285.

60: Wiek J, Newsom R, Kohner E. Role of diabetologist in evaluating diabetic
retinopathy. Diabetes Care. 1991 Nov;14(11):1113. PubMed PMID: 1797503.

61: Sullivan PM, Parfitt VJ, Jagoe R, Newsom R, Kohner EM. Effect of meal on
retinal blood flow in IDDM patients. Diabetes Care. 1991 Aug;14(8):756-8. PubMed
PMID: 1954814.

62: Newsom RS, Rassam SM, Kohner EM. The effect of beta blockers on retinal blood
flow in diabetic patients. Eur J Ophthalmol. 1991 Jul-Sep;1(3):131-6. PubMed
PMID: 1841669.

63. Costen MT, Newsom R et al. Response to goldsmith et Al.
Eye. 2006 Sep;20(9):1105. Epub 2005 Nov 18.

Review articles

64. Screening for Macular degeneration. Krishappa K, Newsom RSB. Optician 6044:231: 28-32. 2006.
65. Macular case histories. Newsom RSB Optician 2006
66. New treatments for Choroidal Neovascularisation. Newsom RSB, Krishappa K. Optician 2006.
67. Management of red dots on the retina. S Kahandadia and Newsom RSB. Optician 2008.
68. Management of white dots on the retina S Kahandadia, RSB Newsom Optician 2008.

Oxford General Practice Library (OGPL) – Oxford University Press 2007

69. OGPL ENT and Ophthalmology RSB Newsom and Hazel Everitt. ISBN-13: 978-0-19- 929805-1 (with Publisher).
70. OGPL Emergencies in Primary Care (Ophthalmic Section).
71. OGPL Child Health (Ophthalmic Section).
72. OGPL Endocrine Problems (Ophthalmic Section).